Journal article

The future burden of oesophageal and stomach cancers attributable to modifiable behaviours in Australia: a pooled cohort study

MA Laaksonen, S Li, K Canfell, RJ MacInnis, GG Giles, E Banks, JE Byles, DJ Magliano, JE Shaw, TK Gill, V Hirani, RG Cumming, P Mitchell, M Bonello, BA Adelstein, AW Taylor, K Price, CM Vajdic

British Journal of Cancer | SPRINGERNATURE | Published : 2023

Abstract

Background: We quantified the individual and joint contribution of contemporaneous causal behavioural exposures on the future burden of oesophageal and stomach cancers and their subtypes and assessed whether these burdens differ between population groups in Australia, as such estimates are currently lacking. Methods: We combined hazard ratios from seven pooled Australian cohorts (N = 367,058) linked to national cancer and death registries with exposure prevalence from the 2017–2018 National Health Survey to estimate Population Attributable Fractions (PAFs) with 95% confidence intervals (CIs), accounting for competing risk of death. Results: Current and past smoking explain 35.2% (95% CI = 11..

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Grants

Awarded by Cancer Council Victoria


Funding Acknowledgements

This work was supported by the National Health and Medical Research Council of Australia (ID1060991). The National Health and Medical Research Council of Australia also supported MAL (ID1053642), KC (ID1082989), EB (ID1136128), JES (ID1079438) and DJM (ID1118161). MAL was additionally supported by the Cancer Institute New South Wales (ID13/ECF/1-07, 2019/CDF1022).